The Substance
The Substance

Storyline

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Cast
Demi Moore
Demi Moore
Elisabeth
Margaret Qualley
Margaret Qualley
Sue
Dennis Quaid
Dennis Quaid
Harvey
Edward Hamilton-Clark
Edward Hamilton-Clark
Fred
Gore Abrams
Gore Abrams
Oliver
Oscar Lesage
Oscar Lesage
Troy
Christian Erickson
Christian Erickson
Man at Diner
Robin Greer
Robin Greer
Male Nurse
Tom Morton
Tom Morton
Doctor
Hugo Diego Garcia
Hugo Diego Garcia
Diego - Boyfriend
Daniel Knight
Casting Director
Jonathon Carley
Jonathon Carley
Assistant Casting Director
Jiselle Henderkott
Jiselle Henderkott
Girl Auditioning
Akil Wingate
Akil Wingate
TV Host
Vincent Colombe
Vincent Colombe
Man in Suit #1 - Harvey's Office
Billy Bentley
Billy Bentley
Man in Suit #2
Lennard Ridsdale
Man in Suit #3
Jordan Ford Silver
Assistant Director - Pump It Up Show
Oscar Salem
Oscar Salem
2nd Assistant Director - Pump It Up Show
Viviane Bossina
Sue's Assistant
Matthew Luret
Matthew Luret
Floor Runner
Jana Bittnerová
Jana Bittnerová
Maria
Olivier Raynal
Olivier Raynal
Alan - 2nd Agent
Tiffany Hofstetter
Tiffany Hofstetter
Stylist
Nicolas Royer
Guy in the Elevator
Nathan Rippy
Nathan Rippy
Assistant Director - New Year's Eve Show
Manon Arizmendi
Little Girl - New Year's Eve Show
Virginie Kotlinski
Mother - New Year's Eve Show
Brett Gillen
Director of Photography - New Year's Eve Show
Charlotte Marquardt
Charlotte Marquardt
Screaming Woman
Léa Hengl
Screaming Woman
Gaëlle Raymond
Gaëlle Raymond
Screaming Woman
Claire Lemaire
Screaming Woman
Lila Boughoufala
Screaming Woman
Aurélien Lorgnier
Screaming Man
Ivan Sellier
Ivan Sellier
Screaming Man
Philip Schurer
Philip Schurer
Screaming Man
Christian Bourmier
Shareholder
Martin Graham
Shareholder
Christian Bordeleau
Christian Bordeleau
Shareholder
Patrick Hamel
Shareholder
Didier D'Hondt
Shareholder
Jacques-Yves Dorges
Shareholder
Jean-Claude Matthey
Shareholder
Olivier Jarcin
Shareholder
Jean-Luc Magneron
Shareholder
Charlotte Murray
Allison - Diner Waitress
Aaron Kahn
Greeting Person
Gabriela Arnon
Greeting Person
Nancy Josephson Lahoussine
Greeting Person
Andrew Eldridge
Greeting Person
Denise Powers
Denise Powers
Greeting Person
Bryan Jones
Greeting Person
Adam Carage
Happy Birthday Person
Maria McClurg
Maria McClurg
Happy Birthday Person
Andrew Desmond
Andrew Desmond
Happy Birthday Person
Rebecca Lafont
Happy Birthday Person
Laura Puech
Laura Puech
Isabella
Ryan Chidester
Ryan Chidester
Stagehand
Céline Vogt
Céline Vogt
Elisabeth (Young) - Walk of Fame
Yannick Guérin
Clumsy Burger Guy - Walk of Fame
Jean Miel
Worker Walk of Fame
Paul Descoings
Worker Walk of Fame
Benoit Lévêque
Worker Walk of Fame
Arthur Molinet
Cocktail Bartender
Manon Sachot
Cocktail Lounge Couple
Bastien Jorelle
Cocktail Lounge Couple
Kelly Hoarau
Female Assistant - Towel
Michel Juskiewicz
George - Harvey's Friend
Louise Greggory
Louise Greggory
Restaurant Waitress
Christophe Sartirano
Guy Looking at Sue
Florent Torres
Guy Looking at Sue
Romain Caldeira
Billboard Technician
Barthelemy Thomas
Billboard Technician
Axel Baille
Photographer
Ashley Lambert
Ashley Lambert
Additional Voices
Ranjani Brow
Ranjani Brow
Additional Voices
Chase Fein
Additional Voices
Shane Sweet
Shane Sweet
Additional Voices
William Calvert
Additional Voices
Michael Corbett
Michael Corbett
Additional Voices
Stephen Apostolina
Stephen Apostolina
Additional Voices
Yann Bean
Yann Bean
The Substance (voice)
Matthew Géczy
Matthew Géczy
Bob Haswell (uncredited)
Namory Bakayoko
Namory Bakayoko
Silhouette (uncredited)
Gregory Defleur
Happy Birthday Person (uncredited)
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